Intravital fluorescent imaging of angiogenesis

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Intravital Imaging of Osteogenesis and Angiogenesis in Repair and Regeneration

Chunlan Huang, Vince Ness, Edward B Brown, Xinping Zhang University of Rochester Medical Center, Rochester, NY [email protected] INTRODUCTION Bone defect healing is a progenitor cell-driven tissue morphogenetic process characterized by coordinated osteogenesis and angiogenesis at the site of repair. The progenitor cells dynamics and spatiotemporal regulation of bone defect repai...

متن کامل

Intravital Imaging

Until recently, the idea of observing life deep within the tissues of a living mouse, at a resolution sufficient to pick out cellular behaviors and molecular signals underlying them, remained a much-coveted dream. Now, a new era of intravital fluorescence microscopy has dawned. In this Primer, we review the technologies that made this revolution possible and demonstrate how intravital imaging i...

متن کامل

Color-coded fluorescent protein imaging of angiogenesis: the AngioMouse models.

We have utilized multicolored fluorescent proteins to develop three imaging models of tumor angiogenesis. In one model, the nonluminous induced capillaries are clearly visible by contrast against the very bright tumor green fluorescent protein (GFP) fluorescence examined either intravitally or by whole-body imaging in real time. Intravital images of an orthotopic model of human pancreatic tumor...

متن کامل

Intravital imaging of phagocyte recruitment.

Extravasation of neutrophils and monocytes is a hallmark event in acute and chronic inflammation. Owing to recent improvements in optical imaging techniques, the classical leukocyte extravasation cascade has been refined with intermediate steps being added. Further studies have shown tissue specific leukocyte recruitment patterns, thus allowing for more selective targeting. Here we focus on rec...

متن کامل

Whole-body and intravital optical imaging of angiogenesis in orthotopically implanted tumors.

The development of drugs for the control of tumor angiogenesis requires a simple, accurate, and economical assay for tumor-induced vascularization. We have adapted the orthotopic implantation model to angiogenesis measurement by using human tumors labeled with Aequorea victoria green fluorescent protein for grafting into nude mice. The nonluminous induced capillaries are clearly visible against...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis

سال: 2013

ISSN: 0915-7441,1880-8808

DOI: 10.2491/jjsth.24.582